Pleiotropic Effects of Statins and Their. Clinical Significance. John C. LaRosa, MD. As the clinical trials that established the lipid- lowering beneficial effects of
12 Dec 2019 However, genes are often pleiotropic, meaning they produce multiple effects in the body. Identifying gene variants that influence the risk for
How do you use pleiotropic in a sentence? What are synonyms for pleiotropic? 2017-07-25 Define pleiotropic. pleiotropic synonyms, pleiotropic pronunciation, pleiotropic translation, English dictionary definition of pleiotropic.
American Heritage® Dictionary of the English Language, Fifth Edition. Pleiotropism is a central term in developmental genetics. In pleiotropism, a single gene affects a number of phenotypic traits in the same organism. These pleiotropic effects often seem to be unrelated to each other. Pleiotropy is a condition in which a single gene influences more than one phenotypic trait in an organism. A phenotypic trait is any observable trait, in contrast to a genotypic trait, which is involved with the genetic composition of an organism. Pleiotropic cytokine: cytokine that affects the activity of multiple cell types.
Define pleiotropic. pleiotropic synonyms, pleiotropic pronunciation, pleiotropic translation, English dictionary definition of pleiotropic. also plei·ot·ro·pism n. Biology The production of diverse effects,
Fenotyper är egenskaper som uttrycks fysiskt såsom färg, pleiotropy. Situationen där en viss gen har en effekt på flera olika egenskaper. By: Matilda03 (Stockholm, Sweden).
Pleiotropy is defined as the phenomenon in which a single locus affects two or more distinct phenotypic traits. The term was formally introduced into the literature by the German geneticist Ludwig Plate in 1910, 100 years ago. Pleiotropy has had an important influence on the fields of physiological and medical genetics as well as on evolutionary biology. Different approaches to the study of
Kemisk struktur. Word. Genetic Pleiotropy. Definition Pleiotropy Definition. Vid pleiotropi kontrollerar en gen uttrycket av flera fenotypiska egenskaper. Fenotyper är egenskaper som uttrycks fysiskt såsom färg, pleiotropy. Situationen där en viss gen har en effekt på flera olika egenskaper.
How to say pleiotrop
What is the definition of pleiotropic? What is the meaning of pleiotropic? How do you use pleiotropic in a sentence?
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How to pronounce, definition audio dictionary. How to say pleiotrop What is the definition of pleiotropic? What is the meaning of pleiotropic? How do you use pleiotropic in a sentence?
[Greek pleiōn, more; see pelə- in Indo-European roots + -tropism.] plei′o·tro′pic (plī′ə-trō′pĭk, -trŏp′ĭk) adj. American Heritage® Dictionary of the English Language, Fifth Edition. 2017-07-25 · That means the gene product is used in many types of cells in different tissues. Sometimes, the gene product may act as a signaling molecule, affecting the functions of many tissues.
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The aim of this article is to survey the pleiotropic e ects of niacin on Concomitantly, it led to a mild increase in MPV (mean platelet. volume)
Lesseur, Corina Remarks on the relationship between pleiotropy and evolvability. TF Hansen. Biosystems 69 Measurement and meaning in biology. D Houle, C Pélabon, GP av HJ Sivertsen · 2014 — dominant meaning that both the heterozygous and homozygous dogs show the merle color phenotype.
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2021-04-13 · Pleiotropy definition: the condition in which a single gene exerts simultaneous effects on more than one | Meaning, pronunciation, translations and examples
av JT Beasley · 2019 · Citerat av 27 — any pleiotropic effects that may negatively impact on plant phenotype. The geometric mean expression of three housekeeping genes: Antagonistisk pleiotropi fokuserar på förekomsten av genmutationer som har fördelar tidigt i livet och nackdelar senare i livet. Pleiotropi Definition.
Genome-wide association meta-analysis identifies pleiotropic risk loci for Additionally, three previously unknown loci reached suggestive significance
Pleiotropy means that a single gene affects two or more characters. In the context of life history evolution, pleiotropy means that a single gene affects the fitness Pleiotropy is a genetic disorder caused when one gene influences two or more apparently unrelated phenotypic traits. Explore more about Pleiotropy at BYJU'S. Pleiotropy is the well-established phenomenon of a single gene affecting multiple traits. It has long played a adjective.
These expressed traits may or may not be related. Pleitropy was first noticed by geneticist Gregor Mendel, who is known for his famous studies with pea plants. By definition, pleiotropy is a situation in which one gene controls for the expression of multiple phenotypic traits. These traits don’t have to be clearly linked, i.e., eye shape and eye color, but can instead be completely unrelated. the phenomenon of one gene being responsible for or affecting more than one phenotypic characteristic. [ pli-ot´rŏ-pe] the production by a single gene of multiple phenotypic effects. The term is often used to refer to a single gene defect that is expressed as problems in multiple systems of the body, such as in osteogenesis imperfecta, where the gene causes defects in several different systems that contain collagen.